NaviGRANT

NIH Grant and Contract Award Codes

Overview

Each NIH Grant and Contract has a unique set of numbers and letters that identify it. Knowing this code enables you to understand whether the award is brand new or a renewal of an ongoing project. It also helps understand what type of project it is whether a basic research project, training, or a capital building project. Knowing more about a particular project will help you prioritize your investigation and contacts. The following information, sourced from NIH, is a practical compilation to give you the insight about the nature of the grants in which you are most interested.

Quick Links

NIH Grant Awards

Numbering System Explanation

Agreement Type Codes (first number in Grant)

Activity Code Titles

Activity Code Program Details

NIH Contract Awards

Numbering System Explanation

Agreement Type Codes (first number in Contract)

Activity Code Titles

Activity Code Program Details

NIH GRANT AWARD IDENTIFICATION NUMBERING SYSTEM

The grant identification number (3ROICA12921-04S1A1) consists of several parts, each having a specific meaning. The following example shows the parts of an ID number assigned to an amendment (A1) to a supplemental (Type 3) application for a traditional research project (R01) referred to the National Cancer Institute (CA). The number further identifies the application serially as the 12921st new proposal submitted to the NCI, and indicates that this is the first supplemental application (S1) to the fourth year (-04) of support to this project.

Application Activity Administering Serial Suffixes

Type Code Organization Number Grant Year Other1

3 R01 CA 12921 - 04 S1A1

Application Type Code - A single-digit code identifying the type of application received and processed. In the example above, the "3" indicates that this is a supplemental request for additional funds. Type code translations are listed in Table 1.

Activity Code - A three-digit code identifying a specific category of extramural activity. All current activity code titles are listed here. Activity code definitions are provided here.

Administering Organization Code - A two-letter code identifying the first major-level subdivision. In the example above, "CA" refers to the National Cancer Institute.

Serial Number - A five-digit number generally assigned sequentially to a series within an Institute, Center, or Division. *As grant applications for ICs reach the 99999 five-digit threshold, the ICs will begin using six-digit serial numbers. Currently the National Cancer Institute is the only IC using the six-digit serial number.

Suffixes - A field composed of the following components:

GRANT YEAR - A two-digit number indicates the actual budget period of a project. The grant year number (01, 02, etc.) is preceded by a dash to separate it from the serial number; e.g., AI 12345-02 or CA 00900-04. The grant year number is increased by one for each succeeding renewal year. Thus, the -02 and -04 year suffixes above identify grants in their second and fourth years.

SUPPLEMENT - The letter "S" and related number identify a particular supplemental record; e.g., S1, S2. Supplement designations follow the grant year or the amendment designation, as the case may be; e.g., AI 12345-01S1 and CA 00900-04A1S2.

AMENDMENT - The letter "A" and related number identify each amended application e.g., A1, A2, etc. Amendment designations follow the grant year or the supplement designation, as the case may be; e.g., DE 34567-02A1 and HL 45678-01S1A2.

ALLOWANCE - The letter "X" and related number identify a fellowship's institutional allowance record. Allowance designations also follow the grant year or other designation; e.g., AG 12345-01X1 and HD 12345-02S1X2.

CONTRACT IDENTIFICATION NUMBERING SYSTEM

The contract identification number consists of five parts, each having a distinct meaning. Its elements are structured as follows:

Type of Activity Administering Serial Modification

Action Code Organization Number Number

1 N01 HV 20002 - 000

Type of Action Code - A single-digit code identifying the type of contract transaction. In the above example, "1" indicates a new contractual agreement. Contract type codes and definitions are listed on page 5.

Activity Code - A three-digit code denoting NIH research and research-related contracts. There are seven active research contract activities (N01, N02, N03, N41, N42, N43 and N44), which are listed in on page 7.

Administering Organization Code - A two-letter code identifying the first major subdivision. In the example above, "HV" refers to the National Heart, Lung, and Blood Institute's Division of Heart and Vascular Diseases. For certain activities, large DHHS organizations with Bureau status may use a first-major-division-level code, as in this example of a contractual agreement awarded by NHLBI through its Division of Heart and Vascular Diseases.

Serial Number - A five-digit number assigned by the Contracting Office to number sequentially all contracts executed. The first digit indicates the fiscal year in which the contract was initially awarded (e.g., 20002 indicates FY 1992). The last four digits, 0002, indicate the serial number. This is the second new contract awarded by the NHLBI's Division of Heart and Vascular Diseases (HV) in FY 1992.

Modification Number - Following the serial number and separated from it by a dash (-) is the modification number, a two-digit number that indicates the number of modifications of the contract. Modification numbers are assigned sequentially from 00 to 99; the number "00" indicating a new contract; "01," the first modification; "02," the second, etc.

NIH GRANT TYPES - DEFINITION CODES

Code

1 New - Request for Department of Health and Human Services support of a project that has not yet been funded.

2 Competing Continuation - Request for an additional term of support based on a funded previous project; must compete for available funds.

3 Supplement - Request for additional funds for a current award, to cover increased costs (noncompeting) or to expand the scope of work (competing).

4 Extension - Request for additional funds beyond the years previously awarded; limited to certain activities, including MERIT (R37) and certain Fellowship (F) and Career (K) awards. These F and K applications do not compete for funds. R37's do require National Advisory Council review.

5 Noncompeting Continuation - Request to pay next budget increment of a current award; does not compete for available funds.

6 Change of Institute or Division - Request for support (cf. Type 1) of a fellowship or training project that has been transferred from one ICD to another.

7 Change of Grantee or Training Institution - Request for support of a funded project that has been transferred from one grantee or training institution to another.

8 Change of Institute or Division - Noncompeting continuation (cf. Type 5) that has been transferred from one ICD to another.

9 Change of Institute or Division - Competing continuation (cf. Type 2) that has been transferred from one ICD to another.

NIH CONTRACT TRANSACTION TYPES – DEFINITION CODES

Code

1 New Contract - New work that defines the specifications, conditions, and negotiated clauses pertaining to a contractual agreement between the Government and a contractor. If any prior agreement exists with the contractor, the contractual document sets forth the scope of work, price, delivery, and additional matters peculiar to the particular procurement, and incorporates by reference or appends the negotiated clauses agreed upon in the prior agreement.

2 Renewal - Supplemental agreement to an existing contract with the incumbent contractor that provides for the performance of additional work similar or identical in nature to that previously required, obligates additional funds, and extends the performance period a minimum of six months (usually one year).

3 Modification - Change Order or Supplemental Agreement not meeting the requirements for a renewal as shown above; however, alters or amends one or more provisions of an existing contract (i.e., extensions of less than six months, overhead adjustments, and/or obligation of additional funds with or without extending the contract).

4 Letter Contract - Written preliminary contractual document that authorizes immediate commencement of work and stipulates maximum fund obligations that may be incurred prior to negotiation of a definitive contract. A letter contract will be superseded by a definitive contract at the earliest possible date, usually within 90 days.

5 Continuation of an Incrementally Funded Contract - Supplemental Agreement that allocates funds for the next increment of work to be performed under a multiple-year, incrementally funded contract, and stipulates the additional time period covered by such funds. The code should not be used to report contract extensions that do not require additional funds to cover the extensions (see Code 3 above).

6 Task Orders and Subsequent Modifications (Relating to Existing Basic Ordering Agreements) - An order placed under an existing Basic Ordering Agreement that specifies the delivery schedule and the obligation of funds. Code 6 is used to report both the initial Task Order and any subsequent modifications to the Task Orders.

7 Exercise of Option - Action taken to implement the Government's right to require the contractor to accomplish work under the contract as negotiated in the original contract. Further negotiation is not necessary, since the original contract included the potential requirement.

ACTIVITY CODE TITLES

Code

Research Construction Programs

C 06 Research Facilities Construction Grants

Training Projects

D 43 International Training Grants in Epidemiology

D 71 International Training Program Planning Grant

D P1 NIH Director’s Pioneer Award (NDPA)

Fellowship Programs

F 05 International Research Fellowships (FIC)

F 06 Senior International Fellowships (FIC)

F 30 Individual Predoctoral NRSA for M.D./Ph.D. Fellowships (ADAMHA)

F 31 Predoctoral Individual National Research Service Award

F 32 Postdoctoral Individual National Research Service Award

F 33 National Research Service Award for Senior Fellows

F 34 MARC (NRSA) Faculty Fellowships

F 37 Medical Informatics Fellowship (NLM)

F 38 Applied Medical Informatics Fellowship (NLM)

Resource Programs

G 07 Resources Improvement Grant (NLM)

G 08 Resources Project Grant (NLM)

G 11 Extramural Associate Research Development Award (EARDA)

G 12 Research Centers in Minority Institutions Award

G 13 Health Sciences Publication Support Awards (NLM)

G 20 Grants for Repair, Renovation and Modernization of Existing Research Facilities

Community Service Programs

H D1 Demonstration for Prevention of Alcohol and Other Drug Abuse Among High-Risk Youth (SAMHSA)

H D5 Demonstrations: Community-Based Mental Health Services for Adults with Serious Mental Illness and Children with Serious Emotional Disturbances (SAMHSA)

H S5 Child Mental Health Services Initiative: Comprehensive Community Mental Health Services for Children and Adolescents with Serious Emotional Disturbances (SAMHSA)

H 13 Conferences (SAMHSA)

H 79 Mental Health and/or Substance Abuse Services Grants (SAMHSA)

Research Career Programs

K D1 Mental Health and/or Substance Abuse Services Demonstration Grants (SAMHSA)

K 01 Research Scientist Development Award - Research & Training

K 02 Research Scientist Development Award - Research

K 04 Modified Research Career Development Award

K 05 Research Scientist Award

K 06 Research Career Award

K 07 Academic/Teacher Award

K 08 Clinical Investigator Award

K 11 Physician Scientist Award (Individual)

K 12 Physician Scientist Award (Program)

K 14 Minority School Faculty Development Award

K 15 Dentist Scientist Award (Individual)

K 16 Dentist Scientist Award (Program)

K 17 Research Career Re-Entry Program

K 18 Career Enhancement Award

K 20 Scientist Development Award for Clinicians

K 21 Scientist Development Award

K 22 Career Transition Award

K 23 Mentored Patient-Oriented Research Career Development Award

K 24 Midcareer Investigator Award in Patient-Oriented Research

K 25 Mentored Quantitative Research Career Development Award

K 26 Midcareer Investigator Award in Biomedical and Behavioral Research

K 30 Clinical Research Curriculum Award (CRCA)

L 30 Loan Repayment Program for Clinical Researchers (OD-LRO)

L 32 Loan Repayment Program for Clinical Researchers from Disadvantaged Backgrounds (OD-LRO)

L 40 Loan Repayment Program for Pediatric Research (OD-LRO)

L 50 Loan Repayment Program for Contraception and Infertility Research (OD-LRO)

L 60 Loan Repayment Program for Health Disparities Research (OD-LRO)

General Clinical Research Centers Programs

M 01 General Clinical Research Centers (NCRR)

Research and Development-Related Contracts

N 01 Research and Development Contracts

N 02 Resource and Support Contracts - Awarded in the ICD

N 03 Station Support Contracts - Awarded by the Division of Procurement

N 43 Small Business Innovation Research - Phase I (Contract)

N 44 Small Business Innovation Research - Phase II (Contract)

Research Program Projects and Centers

P 01 Research Program Projects

P 20 Exploratory Grants

P 30 Center Core Grants

P 40 Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Material Resource Grants (NCRR)

P 41 Biotechnology Resource Grant Program

P 42 Hazardous Substances Basic Research Grants Program (NIEHS)

P 50 Specialized Center

P 51 Primate Research Center Grants (NCRR)

P 60 Comprehensive Center

P 79 Community Action Grants for Health Service System Change (SAMHSA)

Research Projects

R C1 NIH Challenge Grants and Partnerships Program - Phase I (NIAID)

R 01 Research Project

R 03 Small Research Grants

R 09 Scientific Evaluation

R 10 Cooperative Clinical Research (Grants)

R 13 Conferences

R 15 Academic Research Enhancement Awards (AREA)

R 18 Research Demonstration and Dissemination Projects

R 21 Exploratory/Developmental Grants

R 23 New Investigator Research Awards

R 24 Resource-Related Research Projects

R 25 Education Projects

R 29 First Independent Research Support and Transition (FIRST) Award

R 33 Exploratory/Developmental Grants Phase II

R 34 Clinical Trial Planning Grant

R 35 Outstanding Investigator Grants

R 36 Dissertation Award

R 37 Method to Extend Research in Time (MERIT) Award

R 41 Small Business Technology Transfer (STTR) Grants - Phase I

R 42 Small Business Technology Transfer (STTR) Grants - Phase II

R 43 Small Business Innovation Research Grants (SBIR) - Phase I

R 44 Small Business Innovation Research Grants (SBIR) - Phase II

R 55 James A. Shannon Director's Award

R 56 High Priority, Short Term Project Award

R 84 Foreign Currency Research Program (PL-480)

Research-Related Programs

S 03 Minority High School Student Research Apprentice Program (NCRR)

S 06 Minority Biomedical Research Support - MBRS

S 07 Biomedical Research Support Grants (NCRR)

S 10 Biomedical Research Support Shared Instrumentation Grants (NCRR)

S 11 Minority Biomedical Research Support Thematic Project Grants

S 14 Minority Biomedical Research Support Grant Program for Undergraduate Colleges

S 15 Small Instrumentation Grants Program

S 20 Specialized Integrated Core Facilities

S 21 Research and Institutional Resources Health Disparities Endowment Grants – Capacity Building

S 22 Research and Student Resources Health Disparities Endowment Grants – Educational Programs

Training Programs

TU2 Institutional National Research Service Award with Involvement of NIH Intramural Faculty (OD)

T 01 Graduate Training Program

T 06 Minority Supplements to Clinical Training Grants (SAMHSA)

T 09 Scientific Evaluation

T 14 Conferences

Training Programs

T 15 Continuing Education Training Program

T 16 HIV/AIDS Education for Mental Health/Substance Abuse Care Providers

T 22 Institutional Research Fellowships

T 26 Faculty Development Grants for Preventing/Treating Alcohol, Tobacco and Other

Drug Abuse

T 32 Institutional National Research Service Award

T 34 MARC Undergraduate NRSA Institutional Grants

T 35 NRSA Short-Term Research Training

T 36 MARC Ancillary Training Activities (Grant)(NIGMS)

T 37 Minority International Research Training Grants (FIC)

T 90 Interdisciplinary Research Training Award (NIDDK)

Cooperative Agreements

U C1 NIH Challenge Grants and Partnerships Program - Phase II - Cooperative Agreements (NIAID)

U C6 Construction Cooperative Agreement

U D1 Mental Health and/or Substance Abuse KD&A Cooperative Agreements (SAMHSA)

U D3 CMHS/CSAT Collaborative Demonstration Program for Homeless Individuals with Substance Abuse Disorders and Co-occurring Mental Illness--Cooperative Agreements (SAMHSA)

U D5 HIV/AIDS Mental Health Services Demonstration Program Cooperative Agreements

U D7 Employment Intervention Demonstration Cooperative Agreements

U D8 Development and Implementation of Criminal Justice Treatment Networks--Demonstration Cooperative Agreements

U D9 CMHS/CSAT Collaborative Demonstration Program to Prevent Homelessness-Cooperative

Agreements (SAMHSA)

U H1 HBCU Research Scientist Award (NHLBI)

U R1 Cooperative Agreements for Resources and Technical Assistance Projects to Support Mental Health and Substance Abuse Services

U R4 The Effectiveness for Cannabis (Marijuana) Dependency--Cooperative Agreements (SAMHSA)

U R5 Evaluating Utility and Cost Effectiveness of Wrap Around Services for Clients in Non-Residential Substance Abuse Treatment Programs--Cooperative Agreements (SAMHSA)

U R6 Prevention Intervention Research on Substance Abuse in Children--Cooperative Agreements (SAMHSA)

U R7 Managed Care and Vulnerable Populations--Cooperative Agreements (SAMHSA)

U S2 Improving the Health Status of and Services to Minorities and Disadvantaged People--Cooperative Agreements (OASH)

U 01 Research Project (Cooperative Agreements)

U 09 Scientific Review and Evaluation (Cooperative Agreements)

U 1D Invention Model for HIV/AIDS High-Risk Behavior Prevention for Adolescents and Women--Cooperative Agreements

U 1E Effectiveness of Housing Approaches for Persons With Serious Mental Illness--

Cooperative Agreements

U 1F Substance Abuse Prevention: Assessment and Coordination of Information and Technologies-- Cooperative Agreements (SAMHSA)

U 1G Criminal Justice Interventions Involving Co-occurring Mental Illness and Substance Abuse Disorders--Cooperative Agreements (SAMHSA)

U 1H Integration of Mental Health and Substance Abuse Prevention or Treatment with Primary Health Care -Cooperative Agreements (SAMHSA)

U 1J Substance Abuse Centers for the Application of Prevention Technologies--Cooperative Agreements (SAMHSA)

U 1K Workplace Managed Care for Substance Abuse Prevention and Early Intervention--Cooperative Agreements (SAMHSA)

U 1S Emergency Disaster Relief Relating to SAMHSA Programs--Cooperative Agreements

U 10 Cooperative Clinical Research (Cooperative Agreements)

U 13 Conference (Cooperative Agreement)<Reestablished and definition revised>

U 18 Research Demonstration (Cooperative Agreements)

U 19 Research Program (Cooperative Agreement)

U 2R International Training Cooperative Agreement

U 2T Substance Abuse System Technical Assistance to States Through NASADAD (Cooperative Agreements) SAMHSA

U 24 Resource-Related Research Project (Cooperative Agreements)

U 41 Biotechnology Resource (Cooperative Agreements)

U 42 Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials Resource Cooperative Agreements (NCRR)

U 43 Small Business Innovation Research (SBIR) Cooperative Agreements - Phase I

U 44 Small Business Innovation Research (SBIR) Cooperative Agreements - Phase II

U 45 Hazardous Waste Worker Health and Safety Training Cooperative Agreements (NIEHS)

U 54 Specialized Center (Cooperative Agreements)

U 56 Exploratory Grants (Cooperative Agreements) (NCI)

U 69 AIDS National Education and Training Centers (Cooperative Agreements)

U 76 Area Health Education Centers (Cooperative Agreements) (HRSA)

U 79 Mental Health and/or Substance Abuse Services Cooperative Agreements (SAMHSA)

U 94 Cooperative Agreements: Addiction Treatment and Recovery Systems for Rural, Remote, and Culturally-Distinct Populations (SAMHSA)

U 95 Cooperative Agreements: Drug Abuse Treatment Improvement Projects in Target Cities (SAMHSA)

U 96 Cooperative Agreements: Communications Programs for Prevention of Illegal Drug Use or Illegal Use or Illegal Use/Abuse of Alcohol (SAMHSA)

U 97 Cooperative Agreements: Technical Assistance Centers for the Evaluation of Mental Health System Change (SAMHSA)

U 98 Cooperative Agreements: Clinical Training to Improve Substance Abuse Treatment (SAMHSA)

Inter-Agency/Intra-Agency Agreements

Y 01 NIH Inter-Agency Agreements

Y 02 NIH Intra-agency Agreements

Intramural Research

Z 01 Intramural Research

ACTIVITY CODE PROGRAM DETAILS

Training Projects

D 43 International Training Grants in Epidemiology

To improve and expand epidemiologic research and the utilization of epidemiology in clinical trials and prevention research in foreign countries through support of training programs for foreign health professionals, technicians, and other health care workers.

D 71 International Training Program Planning Grant

To plan for the preparation of an application for a D43 international institutional training grant.

D P1 NIH Director’s Pioneer Award (NDPA)

To support individuals who have the potential to make extraordinary contributions to medical research. The NIH Director’s Pioneer Award is not renewable.

Fellowship Programs

F 05 International Research Fellowships (FIC)

To provide collaborative research opportunities for qualified non-immigrant alien scientists who hold a doctoral degree or its equivalent in one of the biomedical or behavioral sciences.

F 30 Individual Predoctoral NRSA for M.D./Ph.D. Fellowships (ADAMHA)

Individual fellowships for predoctoral training which leads to the combined M.D./Ph.D. degrees.

F 31 Predoctoral Individual National Research Service Award

To provide predoctoral individuals with supervised research training in specified health and health-related areas leading toward the research degree (e.g., Ph.D.).

F 32 Postdoctoral Individual National Research Service Award

To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas.

F 33 National Research Service Awards for Senior Fellows

To provide opportunities for experienced scientists to make major changes in the direction of research careers, to broaden scientific background, to acquire new research capabilities, to enlarge command of an allied research field, or to take time from regular professional responsibilities for the purpose of increasing capabilities to engage in health-related research.

Resource Programs

G 07 Resources Improvement Grant

A non-renewable grant available to health related organizations to establish, expand or improve Internet connectivity and improve access to digital information resources.

G 08 Resources Project Grant (NLM)

A grant available to health-related institutions to improve the organization and management of health related information using computers and networks.

G 11 Extramural Associate Research Development Award (EARDA)

To provide funds to institutions eligible to participate in the NIH Extramural Associates Program for establishing or enhancing an office of sponsored research and for other research infrastructure needs.

G 12 Research Centers in Minority Institutions Award

To assist predominantly minority institutions that offer the doctorate in the health professions and/or health-related sciences in strengthening and augmenting their human and physical resources for the conduct of biomedical research.

G 13 Health Sciences Publication Support Awards (NLM)

To provide short-term assistance for the preparation of book-length manuscripts about important scientific information needed by U.S. health professionals. Grants are awarded for major critical reviews and analyses of historical studies and current developments in informatics, technology, librarianship, and secondary reference materials in the biomedical field. Publication in formats other than print-on-paper (e.g., electronic, film, etc.) are encouraged, as are new and innovative ways of organizing and presenting information. Publication grants do not support journals or other serials and are not suitable for operation of established databases. Work judged to have significant commercial viability will not be supported by these grants

G 20 Grants for Repair, Renovation and Modernization of Existing Research Facilities (NCRR)

To provide funds for major repair, renovation, and modernization of existing research facilities. These facilities may be the clinical research facilities, animal research facilities, and other related research facilities.

Research Career Programs

K 01 Research Scientist Development Award - Research & Training

For support of a scientist, committed to research, in need of both advanced research training and additional experience.

K 02 Research Scientist Development Award - Research

For support of a scientist, committed to research, in need of additional experience.

K 05 Research Scientist Award

For the support of a research scientist qualified to pursue independent research which would extend the research program of the sponsoring institution, or to direct an essential part of this research program

K 06 Research Career Awards

To enable institutions to finance positions favorable to the intellectual growth and research productivity of established investigators of high competence for the duration of their careers.

K 07 Academic/Teacher Award (ATA)

To create and encourage a stimulating approach to disease curricula that will attract high quality students, foster academic career development of promising young teacher-investigators, develop and implement excellent multidisciplinary curricula through interchange of ideas and enable the grantee institution to strengthen its existing teaching program.

K 08 Clinical Investigator Award (CIA)

To provide the opportunity for promising medical scientists with demonstrated aptitude to develop into independent investigators, or for faculty members to pursue research aspects of categorical areas applicable to the awarding unit, and aid in filling the academic faculty gap in these shortage areas within health profession's institutions of the country.

K 12 Physician Scientist Award (Program) (PSA)

For support to a newly trained clinician appointed by an institution for development of independent research skills and experience in a fundamental science within the framework of an interdisciplinary research and development program.

K 14 Minority School Faculty Development Awards

To encourage the development of faculty investigators at minority schools and to enhance their research capabilities in specified health and health related areas.

K 16 Dentist Scientist Award (Program)

To provide support for dentists with a strong commitment to oral health research to develop into independent biomedical investigators. Primarily, for support to a newly trained dentist appointed by an institution for development of independent research skills through a three phase program: advanced basic science development, advanced clinical science development, and a research experience component.

K 18 The Career Enhancement Award

Provides either full-time or part-time support for experienced scientists who wish to broaden their scientific capabilities or to make changes in their research careers by acquiring new research skills or knowledge. Career enhancement experiences supported by this award should usually last no more than one year.

K 22 Career Transition Award

To provide support to outstanding newly trained basic or clinical investigators to develop their independent research skills through a two phase program; an initial period involving and intramural appointment at the NIH and a final period of support at an extramural institution. The award is intended to facilitate the establishment of a record of independent research by the investigator in order to sustain or promote a successful research career.

K 23 Mentored Patient-Oriented Research Career Development Award

To provide support for the career development of investigators who have made a commitment of focus their research endeavors on patient-oriented research. This mechanism provides support for a 3 year minimum up to 5 year period of supervised study and research for clinically trained professionals who have the potential to develop into productive, clinical investigators.

K 24 Midcareer Investigator Award in Patient-Oriented Research

To provide support for the clinicians to allow them protected time to devote to patient-oriented research and to act as mentors for beginning clinical investigators.

K 25 Mentored Quantitative Research Career Development Award

To engender and foster such activities by supporting the career development of investigators with quantitative scientific and engineering backgrounds outside of biology or medicine who have made a commitment to focus their research endeavors on behavioral and biomedical research (basic or clinical). This mechanism is aimed at research-oriented scientists with experience at the level of junior faculty (e.g., early to mid-levels of assistant professor or research assistant professor ranks). This award provides support for a period of mentored study and research for professionals with such backgrounds who have the potential to integrate their expertise with biomedicine and develop into productive investigators.

Examples of quantitative scientific and technical backgrounds outside of biology or medicine considered appropriate for this award include, but are not limited to: mathematics, statistics, computer science, informatics, physics, chemistry, and engineering.

K 26 Midcareer Investigator Award in Biomedical and Behavioral Research

The purpose of the Midcareer Investigator Award in Biomedical and Behavioral Research is to provide grant support for biomedical and behavioral scientists to allow them protected time to devote to their research and mentoring.

K 30 Clinical Research Curriculum Award (CRCA)

The CRCA is an award to institutions and is intended to stimulate the inclusion of high-quality, multi-disciplinary didactic training as part of the career development of clinical investigators. This award is intended to support the development of new didactic programs in clinical research at institutions that do not currently offer such programs or, in institutions with existing didactic programs in clinical research to support or expand their programs or to improve the quality of instruction.

L 30 Loan Repayment Program for Clinical Researchers

To provide for the repayment of the educational loan debt of qualified health professionals involved in clinical research. Qualified health professionals who contractually agree to conduct qualified clinical research are eligible to apply for this program.

L 32 Loan Repayment Program for Clinical Researchers from Disadvantaged Backgrounds

To provide for the repayment of the educational loan debt of qualified health professionals from disadvantaged backgrounds involved in clinical research. Qualified health professionals from disadvantaged backgrounds who contractually agree to conduct qualified clinical research are eligible to apply for this program.

L 40 Loan Repayment Program for Pediatric Research

To provide for the repayment of the educational loan debt of qualified health professionals involved in research directly related to diseases, disorders, and other conditions in children. Qualified health professionals who contractually agree to conduct qualified pediatric research are eligible to apply for this program.

L 50 Loan Repayment Program for Contraception and Infertility Research

To provide for the repayment of the educational loan debt of qualified health professionals (including graduate students) who contractually agree to commit to conduct qualified contraception and/or infertility research.

L 60 Loan Repayment Program for Health Disparities Research

To provide for the repayment of the educational loan debt of qualified health professionals involved in minority health and health disparities research, for the purposes of improving minority health and reducing health disparities. Qualified health professionals who contractually agree to conduct qualified minority health disparities research or other health disparities research eligible to apply for this program.

General Clinical Research Centers Program

M 01 General Clinical Research Centers Program

An award made to an institution solely for the support of a General Clinical Research Center where scientists conduct studies on a wide range of human diseases using the full spectrum of the biomedical sciences. Costs underwritten by these grants include those for renovation, for operational expenses such as staff salaries, equipment, and supplies, and for hospitalization. A General Clinical Research Center is a discrete unit of research beds separated from the general care wards.

Research Program Projects and Centers

P 01 Research Program Projects

For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.

P 20 Exploratory Grants

To support planning for new programs, expansion or modification of existing resources, and feasibility studies to explore various approaches to the development of interdisciplinary programs that offer potential solutions to problems of special significance to the mission of the NIH. These exploratory studies may lead to specialized or comprehensive centers.

P 30 Center Core Grants

To support shared resources and facilities for categorical research by a number of investigators from different disciplines who provide a multidisciplinary approach to a joint research effort or from the same discipline who focus on a common research problem. The core grant is integrated with the center's component projects or program projects, though funded independently from them. This support, by providing more accessible resources, is expected to assure a greater productivity than from the separate projects and program projects.

P 40 Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Material Resource Grants (NCRR)

To develop and support animal (mammalian and nonmammalian) models, or animal or biological materials resources available to all qualified investigators without regard to the scientific disciplines or disease orientations of their research activities or specifically directed to a categorical program. Nonmammalian resources include nonmammalian vertebrates, invertebrates, cell systems, and nonbiological systems.

P 41 Biotechnology Resource Grants

To support biotechnology resources available to all qualified investigators without regard to the scientific disciplines or disease orientations of their research activities or specifically directed to a categorical program area.

P 42 Hazardous Substances Basic Research Grants Program (NIEHS)

To support basic research directed towards understanding and attenuating the public health effects resulting from exposure to hazardous substances, including 1) advanced techniques for detection, assessment and evaluation of the effects on human health of hazardous substances; 2) methods to assess risks to human health presented by hazardous substances; 3) methods and technologies to detect hazardous substances in the environment and 4) basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances. This special program, authorized under Superfund legislation, is for a broadly based, multi-disciplinary research effort which must include biomedical research components and which may include research components related to engineering, hydrogeology, ecology and epidemiology so long as they are linked to basic biomedical science. Each research project is generally under the leadership of an established investigator. The grant can provide support for certain basic resources used by the groups in the program (cores), including an administrative structure for effective coordination.

P 50 Specialized Center

To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

P 51 Primate Research Center Grants (NCRR)

To support centers which include a multidisciplinary and multi-categorical core research program using primate animals and to maintain a large and varied primate colony which is available to affiliated, collaborative, and visiting investigators for basic and applied biomedical research and training.

P 60 Comprehensive Center

To support a multipurpose unit designed to bring together into a common focus divergent but related facilities within a given community. It may be based in a university or may involve other locally available resources, such as hospitals, computer facilities, regional centers, and primate colonies. It may include specialized centers, program projects and projects as integral components. Regardless of the facilities available to a program, it usually includes the following objectives: to foster biomedical research and development at both the fundamental and clinical levels; to initiate and expand community education, screening, and counseling programs; and to educate medical and allied health professionals concerning the problems of diagnosis and treatment of a specific disease.

Research Projects

R 01 Research Project

To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his specific interest and competencies.

R 03 Small Research Grants

To provide research support specifically limited in time and amount for studies in categorical program areas. Small grants provide flexibility for initiating studies which are generally for preliminary short-term projects and are non-renewable.

R 10 Cooperative Clinical Research (Grants)

To support clinical evaluation of various methods of therapy and/or prevention in specific disease areas. These represent cooperative programs between participating institutions and principal investigators, and are usually conducted under established protocols.

R 13 Conference

To support recipient sponsored and directed international, national or regional meetings, conferences and workshops.

R 15 Academic Research Enhancement Awards (AREA)

To support small scale research projects conducted by faculty in primarily baccalaureate degree-granting domestic institutions. Awards are for up to $75,000 for direct costs (plus applicable indirect costs) for periods not to exceed 36 months.

R 18 Research Demonstration and Dissemination Projects

To provide support designed to develop, test, and evaluate health service activities, and to foster the application of existing knowledge for the control of categorical diseases.

R 21 Exploratory/Developmental Grants

To encourage the development of new research activities in categorical program areas. (Support generally is restricted in level of support and in time.)

R 24 Resource-Related Research Projects

To support research projects that will enhance the capability of resources to serve biomedical research.

R 25 Education Projects

For support to develop and/or implement a program as it relates to a category in one or more of the areas of education, information, training, technical assistance, coordination, or evaluation.

R 29 First Independent Research Support and Transition (FIRST) Award

To provide a sufficient initial period of research support for newly independent biomedical investigators to develop their research capabilities and demonstrate the merit of their research ideas.

R 33 Exploratory/Developmental Grants Phase II

The R33 award is to provide a second phase for the support for innovative exploratory and development research activities initiated under the R21 mechanism. Although only R21 awardees are generally eligible to apply for R33 support, specific program initiatives may establish eligibility criteria under which applications could be accepted from applicants demonstrating progress equivalent to that expected under R33.

R 37 Method to Extend Research in Time (MERIT) Award

To provide long-term grant support to investigators whose research competence and productivity are distinctly superior and who are highly likely to continue to perform in an outstanding manner. Investigators may not apply for a MERIT award. Program staff and/or members of the cognizant National Advisory Council/Board will identify candidates for the MERIT award during the course of review of competing research grant applications prepared and submitted in accordance with regular PHS requirements.

R 41 Small Business Technology Transfer (STTR) Grants - Phase I

To support cooperative R&D projects between small business concerns and research institutions, limited in time and amount, to establish the technical merit and feasibility of ideas that have potential for commercialization. Awards are made to small business concerns only.

R 42 Small Business Technology Transfer (STTR) Grants - Phase II

To support in-depth development of cooperative R&D projects between small business concerns and research institutions, limited in time and amount, whose feasibility has been established in Phase I and that have potential for commercialization. Awards are made to small business concerns only.

R 43 Small Business Innovation Research Grants (SBIR) - Phase I

To support projects, limited in time and amount, to establish the technical merit and feasibility of R&D ideas which may ultimately lead to a commercial product(s) or service(s).

R 44 Small Business Innovation Research Grants (SBIR) - Phase II

To support in-depth development of R&D ideas whose feasibility has been established in Phase I and which are likely to result in commercial products or services. SBIR Phase II are considered “Fast-Track” and do not require National Council Review.

R 55 James A. Shannon Director's Award

To provide a limited award to investigators to further develop, test, and refine research techniques; perform secondary analysis of available data sets; test the feasibility of innovative and creative approaches; and conduct other discrete projects that can demonstrate their research capabilities and lend additional weight to their already meritorious applications.

R 56 High Priority, Short Term Project Award

To provide limited interim research support based on the merit of a pending R01 application while applicant gathers additional data to revise a new or competing renewal application. This grant will underwrite highly meritorious applications that if given the opportunity to revise their application could meet IC recommended standards and would be missed opportunities if not funded. Interim funded ends when the applicant succeeds in obtaining an R01 or other competing award built on the R56 grant. These awards are not renewable.

Research-Related Programs

S 06 Minority Biomedical Research Support - MBRS

To strengthen the biomedical research and research training capability of ethnic minority institutions, and thus establish a more favorable milieu for increasing the involvement of minority faculty and students in biomedical research.

S 10 Biomedical Research Support Shared Instrumentation Grants (NCRR)

To make available to institutions with a high concentration of NIH extramural research awards, research instruments which will be used on a shared basis.

S 11 Minority Biomedical Research Support Thematic Project Grants

To promote increased faculty and interdepartmental collaboration through programs that focus on specific research themes or scientific disciplines at developing minority institutions. These grants are intended to strengthen the biomedical research capability in defined areas and to attract other competent biomedical scientists through an improved research environment.

S 21 Research and Institutional Resources Health Disparities Endowment Grants -Capacity Building

To strengthen the research and training infrastructure of the institution, while addressing current and emerging needs in minority health and other health disparities research.

S 22 Research and Student Resources Health Disparities Endowment Grants - Educational Programs

To increase the investment in student-centered programs: to improve the academic success of underrepresented minorities and socio-economically disadvantaged individuals in biomedical and bio-behavioral fields of study.

Training Programs

T 14 Conferences

For support of international and national meetings, conferences and workshops.

T 15 Continuing Education Training Grants

To assist professional schools and other public and nonprofit institutions to establish, expand, or improve programs of continuing professional education, especially for programs of extensive continuation, extension, or refresher education dealing with new developments in the science of technology of the profession.

T 32 Institutional National Research Service Award

To enable institutions to make National Research Service Awards to individuals selected by them for predoctoral and postdoctoral research training in specified shortage areas.

T 34 MARC Undergraduate NRSA Institutional Grants

To enable minority institutions to make National Research Service Awards to individuals selected by them for undergraduate research training in the biomedical and behavioral sciences.

T 35 NRSA Short-Term Research Training

To provide individuals with research training during off-quarters or summer periods to encourage research careers and/or research in areas of national need.

T 36 MARC Ancillary Training Activities (Grant) (NIGMS)

To increase the number of well-trained minority scientists in biomedical disciplines and to strengthen the research and teaching capabilities of minority institutions through a variety of training mechanisms such as visits by experienced scientists to minority institutions or workshops/conferences designed to enhance the research training experience of students/faculty from minority institutions

T 37 Minority International Research Training Grants (FIC)

Institutional training grants awarded to domestic institutions supporting opportunities for biomedical and behavioral research training for minority students and faculty members at foreign sites.

T90 Interdisciplinary Research Training Award

To support comprehensive interdisciplinary research training programs at the undergraduate, predoctoral and/or postdoctoral levels, by capitalizing on the infrastructure of existing multidisciplinary and interdisciplinary research programs.

Cooperative Agreements

U C6 Construction Cooperative Agreement

To provide financial support, substantial programmatic involvement and technical assistance for designing, constructing and commissioning of laboratories to be used as extramural facilities for bio-defense and emerging infectious diseases research.

U H1 HBCU Research Scientist Award

To assist HBCUs in strengthening and augmenting their human resources by recruiting an established research scientist; to enhance the career of the recruited research scientist; and to strengthen other HBCU resources for the conduct of biomedical and/or behavioral research. The recruited research scientist must have received competitive and independent research support.

U 01 Research Project--Cooperative Agreements

To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his specific interest and competencies.

U 09 Scientific Review and Evaluation--Cooperative Agreements

To provide the chairman of an initial review group funds for operation of the review group.

U 10 Cooperative Clinical Research--Cooperative Agreements

To support clinical evaluation of various methods of therapy and/or prevention in specific disease areas. These represent cooperative programs between sponsoring institutions and participating principal investigators, and are usually conducted under established protocols.

U 13 Conference--Cooperative Agreements

To support international, national or regional meetings, conferences and workshops where substantial programmatic involvement is planned to assist the recipient.

U 18 Research Demonstration--Cooperative Agreements

To provide support for testing, by means of a research design, the effectiveness of the transfer and application of techniques or interventions derived from a research base for the control of diseases or disorders or for the promotion of health. The project should be capable of making conclusions which are generalizable to other sites. These are usually cooperative programs between participating principal investigators, institutions, and the sponsoring Institute(s).

U 19 Research Program--Cooperative Agreements

To support a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach. A cooperative agreement research program generally involves the organized efforts of large groups, members of which are conducting research projects designed to elucidate the various aspects of a specific objective. Substantial Federal programmatic staff involvement is intended to assist investigators during performance of the research activities, as defined in the terms and conditions of award. The investigators have primary authorities and responsibilities to define research objectives and approaches, and to plan, conduct, analyze, and publish results, interpretations and conclusions of their studies. Each research project is usually under the leadership of an established investigator in an area representing his/her special interest and competencies. Each project supported through this mechanism should contribute to or be directly related to the common theme of the total research effort. The award can provide support for certain basic shared resources, including clinical components, which facilitate the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence.

U 2R International Training Cooperative Agreement

In cooperation with public and private nonprofit organizations, to improve and strengthen epidemiology, clinical, operational, and health services research capacity in foreign countries through support of training programs.

U 24 Resource-Related Research Projects--Cooperative Agreements

To support research projects contributing to improvement of the capability of resources to serve biomedical research.

U 42 Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Materials Resource Cooperative Agreements (NCRR)

To develop and support animal (mammalian and nonmammalian) model, or animal or biological materials resources available to all qualified investigators without regard to the scientific disciplines or disease orientations of their research activities or specifically directed to a categorical program. Nonmammalian resources include nonmammalian vertebrates, invertebrates, cell systems, and nonbiological systems.

U 44 Small Business Innovation Research (SBIR) Cooperative Agreements - Phase II

To support in-depth development of R&D ideas whose feasibility has been established in Phase I and that are likely to result in commercial products or services.

U 45 Hazardous Waste Worker Health and Safety Training Cooperative Agreements (NIEHS)

To develop, implement, and evaluate programs to train workers who are or may be engaged in activities related to hazardous waste removal, containment, or emergency response.

U 54 Specialized Center--Cooperative Agreements

To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These differ from program project in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes, with funding component staff helping to identify appropriate priority needs